Biohacker Life — Evidence first. Hype never.
Editors' Picks
All articles →Peptides, From First Principles
Retatrutide: What the Trials Actually Show
The 90-Minute Sleep Cycle Rule Is Mostly Wrong
Continuous Glucose Monitors for Non-Diabetics: A Field Report
Caffeine and L-Theanine: The Stack That Survives Scrutiny
I Tracked 400 Nights of Sleep. Five Things Moved the Needle
Peptides
View all →Peptides, From First Principles
The chemistry is settled and genuinely elegant. The marketplace built on top of it is where the evidence stops being uniform — and the word "peptide" does a lot of work hiding that.
Metabolic Health
View all →Retatrutide: What the Trials Actually Show
The trial data is genuinely remarkable, the mechanism is elegant, and the compound is approved in no country on earth. All three of those things are true at once, and most coverage manages only the first.
Sleep
View all →The 90-Minute Sleep Cycle Rule Is Mostly Wrong
Set your alarm for a multiple of ninety minutes and you will wake up refreshed — so the advice goes. The number is an average of a distribution nobody bothered to look at.
Nootropics
View all →Caffeine and L-Theanine: The Stack That Survives Scrutiny
Most nootropic combinations are folklore with a supplement facts panel attached. This one has repeatedly beaten placebo in controlled trials, and the effect is smaller than the internet claims.
Creatine Is Not Just for Lifters. The Cognitive Data, Assessed
The best-evidenced sports supplement of the last thirty years has a second literature attached to it. It is smaller, messier, and more interesting than either its promoters or its critics admit.
Modafinil, Honestly
Twenty years of research, a genuine effect, a real regulatory status, and a set of trade-offs that the productivity-blog framing consistently omits.
Longevity
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Cold Exposure: What Survives Scrutiny
Ice baths have collected an extraordinary set of claims over the last decade. A few of them hold up. One of them is the opposite of what most people believe.
Nutrition
View all →Continuous Glucose Monitors for Non-Diabetics: A Field Report
Ninety days wearing a sensor designed for a disease I do not have. I learned three genuinely useful things and spent about six weeks drawing conclusions from noise.
Time-Restricted Eating After the Big Trials
The mouse data were spectacular. Then the randomised human trials arrived, and the picture became considerably more mundane.
Protein: How Much You Actually Need
The official minimum and the useful target are different numbers, and the gap between them explains most of the internet argument.
Training
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Zone 2 Training Without the Dogma
The physiology is sound. The obsession with staying inside a narrow heart rate band, and the belief that everything else is wasted, is not.
Guest Posts
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Your byline could be here
We take pitches from clinicians, researchers and anyone who has run a self-experiment carefully enough to report it honestly — including the null results.
Pitch an articleMust Read
Peptide Safety, Stated Honestly
For most compounds in this category there is no human safety data at all. That is the headline, not a footnote — and it changes what a safety article can responsibly say.
The Two Clocks
Reconstituting a vial starts two timers that measure completely different things. Almost every storage guide collapses them into one number, and that conflation is where the confusion lives.
Retatrutide: What the Trials Actually Show
The trial data is genuinely remarkable, the mechanism is elegant, and the compound is approved in no country on earth. All three of those things are true at once, and most coverage manages only the first.